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Life Extension

Life Extension Mitochondrial Energy Optimizer with BioPQQ

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120 capsules

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LifeExtension Mitochondrial Energy Optimizer with BioPQQ support optimal mitochondrial biogenesis and function. All cells in our bodies contain tiny organelles called mitochondria that function to produce cellular energy by means of the adenosine triphosphate (ATP) cycle. The number of mitochondria in a cell varies widely by organism and by tissue type. A human cell can have from a few to several thousand mitochondria.

One of the most serious events that causes the loss of cellular vitality is the depletion of mitochondrial energy-producing function. Cells require healthy mitochondrial activity to perform life-sustaining metabolic processes. As mitochondrial function weakens in our cells, so does the vitality of organs such as the heart and brain or in some cases, the entire body.

In order for the mitochondria to create the energy needed to sustain cellular function, fatty acids (which serve as the mitochondria's fuel) must be transported through the cell membrane and into the mitochondria.

Life Extension Mitochondrial Energy Optimizer with BioPQQ not only helps protect delicate cellular structures and enables cells to perform life-sustaining metabolic processes, it also helps generate new mitochondria! This formula is designed to counteract age-related structural and functional changes and promote biogenesis with these unique ingredients:

  • PQQ (Pyrroloquinoline quinone) — this next generation cellular rejuvenator triggers growth of new mitochondria in aging cells … and activates genes involved in protecting delicate structures within the mitochondria.
  • Carnosine — As humans age, their proteins become irreversibly damaged by lethal glycation reactions. Glycation is the cross-linking of proteins or lipids and sugar to form non-functioning advanced glycation end-products (AGEs) in the body, which can lead to alterations of normal cell function. Carnosine is not only the premier anti-glycating agent, but it also protects neurons against reactive and cytotoxic protein carbonyl species associated with normal aging.
  • Luteolin — Unremitting systemic inflammation is involved with virtually every undesirable consequence of aging. Culprits behind inflammatory reactions are pro-inflammatory cytokines, such as interleukin-1 and tumor necrosis factor alpha. Luteolin is a super-potent plant extract that has been shown to suppress these dangerous inflammatory cytokines.
  • Benfotiamine — Benfotiamine blocks multiple destructive biochemical pathways, including AGEs' formation pathway, which is induced by higher than desirable blood glucose levels. Human mortality studies indicate that ideal fasting glucose levels are between 74–85 mg/dL. Yet many aging people have fasting glucose above 90 mg/dL, which is less than optimal. Benfotiamine can activate glucose metabolism and promote already healthy blood glucose levels. In addition, benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage.
  • Pyridoxal 5'-Phosphate — Aging results in the formation of toxic advanced glycation end products throughout the body. Pyridoxal 5'-phosphate is the active form of vitamin B6 that has been shown to protect against both lipid and protein glycation reactions.
  • R-Lipoic Acid — Destructive free radical activity in the mitochondria plays a major role in the loss of cellular vitality. The microencapsu-lated Bio-Enhanced R-lipoic acid facilitates youthful mitochondrial energy output while guarding against free radicals. Two forms of lipoic acid are sold on the supplement market, but R-lipoic acid is far more potent.
  • Acetyl-L-Carnitine Arginate — The amino acid L-carnitine is required to transport fats into the mitochondria to be burned for cellular energy. ArginoCarn Acetyl-L-carnitine arginate is a patented form of carnitine that has been shown in cell cultures to stimulate the growth of neurites.

Taking all of these ingredients separately would be prohibitively expensive. Life Extension Mitochondrial Energy Optimizer with BioPQQ combines all of them in this one comprehensive formulation to promote mitochondrial structure, function and formation.


Take two capsules twice daily, preferably early in the day or all at once upon wakening, or as recommended by a healthcare practitioner.

This product can be taken with or without food.

To ensure product consistency, store tightly closed in a cool, dry place.

Each 4 Capsules Provide:

Vitamin B6 (as pyridoxal 5’-phosphate) 100mg
Sodium 18mg
Carnosine 1000mg
L-Taurine 800mg
Benfotiamine 150mg
R-Lipoic Acid (as microencapsulated Bio-Enhanced stabilized Na-RALA sodium R-lipoate) 150mg
BioPQQ Pyrroloquinoline quinone disodium salt 10mg
Luteolin (high purity luteolin as Pureolin) 8mg

Also contains: Silica, vegetable cellulose (capsule), microcrystalline cellulose, candelilla wax, beeswax, stearic acid, corn starch, acacia gum, calcium silicate. 

Non - GMO

Life Extension

The Life Extension Foundation is the world’s largest membership organization dedicated to investigating every method of extending the healthy human life span and funding anti-aging research. Based on current scientific research, Life Extension is continually formulating and upgrading its science-based multivitamin, vitamin, and nutritional supplement formulas to include the latest novel ingredients that are years ahead of mainstream offerings.

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