I find it most helpful at the Dentist. I take 5 drops about 15 minutes before I go and then again when I come out. Depending on what is done I continue for the next hour then stop. I have had extractions, large replacement fillings, cleans, small fillings. It seems to work for all. Of course it also works for too much Gardening, Cleaning Windows and General aches from other jobs I have overdone.