I don't understand how these little drops in water can help but I have had amazing relief with my arthritic knees. I am able to walk 1500 steps a day unaided where before taking them I was lucky to get to 500. I went off them for 6 days, found I needed them. I read only 6 weeks but will talk to my doctor soon and see what he suggests. Down to only taking them twice a day and it seems to work for me.