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Doctor's Best

SAMe 400mg Double Strength

30 tablets
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Our Price:NZ$65.50
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Product Specialties
GMP Manufactured
Good Ingredients Approved
Heavy Metals Tested
Synthetic Preservative Free
GMO Free
Fragrance Free
Artificial Sweetener Free
Artificial Flavour Free
Artificial Colour Free
Alcohol Free
Dairy Free
Sugar Free
Soy Free
Low Sodium
Egg Free
Ethically Traded
BPA-Free Packaging
Recyclable Packaging
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Mindful Brands
Mindful Brand Doctor's Best is a Mindful Brand. They’re committed to meaningful change that looks after our people and planet. Learn more

Doctor's Best SAMe 400mg Double Strength This is a double-strength SAM-e formula providing 400mg per tablet. Doctor’s Best SAM-e has been shown to support mood, brain health, and mental focus. It is essential for the healthy metabolism of the major brain transmitters’ dopamine, serotonin, and norepinephrine. In addition, SAM-e supports joint comfort and mobility as well as supporting liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human studies published over 40 years.

S-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints, and brain. SAM-e is also required for the synthesis of critical neurotransmitters and hormones.

Doctor’s Best SAM-e uses pharmaceutical grade materials. SAM-e is optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed).

  • Individuals using antidepressant medications should consult with their healthcare practitioner prior to using this product.
  • Individuals diagnosed with Bipolar Disorder should avoid supplementing with SAM-e. 
  • Do not use if pregnant or breastfeeding.
  • May cause gastrointestinal discomfort in a small percentage of people.
  • Always read the label and use as directed. If symptoms persist see your healthcare professional.

 TAPS PP1387

Adults: Take 1 tablet daily away from food, or as recommended by a healthcare practitioner. Do not chew or crush tablet.

Each Tablet Provides:

S-Adenosyl Methionine (from SAM-e tosylate disulfate) 400mg

Other Ingredients: Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide. 

Gluten-free, soy-free, vegetarian and vegan.

  • Double-strength SAM-e formula providing 400mg per tablet
  • SAM-e is one of the most important methyl donors in the central nervous system
  • Supports joint comfort and mobility
  • Supports liver health and detoxification
  • Vegetarian and vegan

What other customers think


5 out of 5
(Out of 3 Total Reviews)
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02-06-2020 17:51:51
02-06-2020 17:51:51
My husband has arthritis in his back and hand. He was skeptical when I bought them but now wouldn't be without them. He commented after two weeks that his joints were much less painful. Great product.

12-08-2019 19:30:21
Great supplement
12-08-2019 19:30:21
Having read up about this product, and experiencing the positive impact on myself, I fully recommend this product. While I am very conscious of the placebo effect of everyday supplements, and without going into details, I\'d just say that I am happy to reorder again and again, making SAM-E one of the few necessities I consider important for my daily well-being.

11-07-2017 23:36:18
Very pleased with this product
11-07-2017 23:36:18
Fantastic product for joint pain and aching muscles
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