I've been taking these for just three weeks experimentally as PMS was making me super irritable and i was worried about excess body hair, i thought maybe my estrogen was low. I could feel tiny cramps from taking just one of these a day and felt reassured that they must be working! However this period I have experienced extremely low, debilitating moods and my period is so, so heavy like it used to be when I was a teenager. I'm completely wiped out! Guess the product isn't the right thing for me and it looks like it has made my estrogen levels too high. It must be a very powerful supplement to have this effect so fast. By all means try it if you are low estrogen I guess!